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KMID : 0858520010050020130
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Journal of the Korean Society of Magnetic Resonance in Medicine
2001 Volume.5 No. 2 p.130 ~ p.137
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Perfusion MR Imaging of Cerebral Gliomas:Comparison with Histologic Tumor Grade
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최충곤/Choong Gon Choi
정애경/김정훈*/강신광†/이호규/Ae Kyung Jung/Jung Hoon Kim*/Shin Kwang Kang†/Ho Kyu Lee
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Abstract
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Purpose: Our purpose was to compare maximum relative cerebral blood volume (rCBV) with histologic grade of cerebral gliomas.
Materials and Methods: First-pass perfusion MR imaging was performed preoperatively in 16 patients with pathologically proven cerebral gliomas (7 glioblastoma, 2 anaplastic astrocytoma, 1 anaplastic oligo-dendroglioma, 5 low-grade astrocytoma, and 1 low-grade oligodendroglioma). Maximum rCBV was com-pared with histologic diagnosis and grade of the tumor.
Results: Maximum rCBVs of glioblastomas were in the range of 433%-1330% (average, 790%), as compared with those of contra-lateral normal white matters. Maximum rCBVs of two non-enhancing anaplastic astrocytomas were 66% and 284%, respectively. Maximum rCBV of one well-enhancing anaplastic oligodendroglioma was 502%. Maximum rCBVs of low-grade astrocytomas were in the range of 80%-369% (average, 202%). Maximum rCBV of one low-grade oligodendroglioma was 1450%, even higher than those of glioblastomas.
Conclusion: Maximum rCBV was higher in glioblastoma than in low-grade astrocytoma without overlap-ping. However, there was no difference of maximum rCBV between non-enhancing anaplastic astrocytoma and low-grade astrocftoma.
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KEYWORD
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Brain, perfusion, Brain, MR, Brain, tumor
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